Examples ======== Six module example ~~~~~~~~~~~~~~~~~~ |image19|\ The TSS is its own module since it doesn’t overlap with other modules. A5, alternative 5’ splice site; A3, alternative 3’ splice site; CE, cassette exon; IR, intron retention; TSS, transcript start site. Output Files ============ *All output files (including summary.tsv) have the following columns:* - Module ID - Unique identifier for the module, where is the nth module found along the gene, scanning from 5’ to 3’. - LSV ID(s): One or two LSV ID(s) separated by semi-colon - Gene Name - Gene ID - Chr - Strand *Each event file also has exon and junction name and coordinate columns:* - Reference Exon Coordinate (if LSVs may be associated with the event) - Exon or Junction Name - Exon or Junction Coordinate *Plus the following columns if E(PSI) voila files provided:* - _E(PSI) - Expected value of the PSI distribution for each junction - _Var(E(PSI)) - Variance of the PSI distribution for each junction - Note: take the square root to obtain the standard deviation of the PSI distribution - <+Two more columns for each input Voila PSI file> *Or, the following if E(dPSI) voila files provided:* - _E(dPSI) - Expected value of the dPSI distribution for each junction - _P(\|dPSI|>=0.20) - Probability \|dPSI|>=0.2 for each junction - Note, ‘0.20’ is the default, but this threshold is specified by `--threshold <#6vjoi6vfq3rx>`__ - _P(\|dPSI|<=0.05) - Probability \|dPSI|<=0.05 for each junction - Note, ‘0.05’ is the default, but this threshold is specified by `--non-changing-threshold <#6oe52jro363h>`__ - __E(PSI) - Expected value of the PSI distribution for each junction - Note: if one of the input files is .voila.psi, the quantifications from the voila.psi file will be displayed, but \*not\* the quantification from the voila.deltapsi file. This is done to avoid having duplicate columns. - __E(PSI) - Expected value of the PSI distribution for each junction - Note: if one of the input files is .voila.psi, the quantifications from the voila.psi file will be displayed, but \*not\* the quantification from the voila.deltapsi file. This is done to avoid having duplicate columns. - <+Five more columns for each input Voila dPSI file> .. |image19| image:: modulizer_media/image14.png :width: 7.5in :height: 1.58333in