new_majiq.Heterogen

class rna_majiq.Heterogen(psi1, psi2, min_experiments_f=0.5, name1='grp1', name2='grp2', show_progress=False)

Compare Psi between two groups of PsiCoverage (independence assumption)

Compare Psi between two groups of PsiCoverage under the assumption that each experiment is independent. Perform null-hypothesis testing on posterior means and/or samples under assumption that underlying values of PSI per experiment are independent and identically distributed (i.i.d.).

Parameters:

• psi1, psi2 (Union[PsiCoverage, PsiGroup]) – PsiCoverage or PsiGroup for the two groups to compare

• min_experiments_f (float) – Number or proportion of experiments required to pass in each group for quantification

• name1, name2 (str) – Names to indicate group identity

• show_progress (bool) – Show progress of intermediate computations required for setting up this object.

__init__(psi1, psi2, min_experiments_f=0.5, name1='grp1', name2='grp2', show_progress=False)

Methods

__init__(psi1, psi2[, min_experiments_f, ...])
approximate_stats([ec_idx, quantiles, ...])	Statistics on means, samples from approximate posteriors
dataset([pvalue_quantiles, use_stats, ...])
events_to_zarr(path, mode[, consolidated])	Save events information to specified path
get_events(introns, junctions)	Construct Events using saved dataset and introns, junctions
raw_stats([ec_idx, use_stats])	Statistics on means, samples from raw posteriors

Attributes

num_connections	Total number of connections over all events
num_events	Total number of events