rna_majiq.SimplifierGroup.add_experiment

SimplifierGroup.add_experiment(sj, min_psi=0.01, minreads_annotated=0.0, minreads_denovo=0.0, minreads_introns=0.0)

Add SJExperiment to simplification group

Add SJExperiment to simplification group. Counts when a junction or intron passes simplification filters with respect to source exon (or target exon)

Parameters:
  • min_psi (float) – An intron or junction passes as a source (or target) only if the percentage of reads assigned to it vs other connections sharing the same source (or target) exon exceeds this value

  • minreads_annotated, minreads_denovo, minreads_introns (float) – A connection can only pass simplifier thresholds if the readrate assigned to it exceeds appropriate value (annotated junction vs denovo junction vs intron)